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Medications usually used to treat ADHD improve the availability in the synapse of two neurotransmitters, dopamine and norepinephrine. Specific neurotransmitters (brain chemicals) are necessary to carry a nerve impulse (message) along a neuropathway (circuit). When a neurotransmitter is not fully available, a message may be stopped short of its intended destination. When this happens, the function regulated by that circuit may not work as well as it should.
On February 21, 2007 The U.S. Food and Drug Administration (FDA) directed the manufacturers of all drug products approved for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) to develop Patient Medication Guides to alert patients to possible cardiovascular risks and risks of adverse psychiatric symptoms associated with the medicines, and to advise them of precautions that can be taken. Recently the American Heart Association (AHA) recommended routine electrocardiograms to be performed before prescribing stimulant medications to children and adolescents for the treatment of ADHD. However, several other professional organizations came to different conclusions. Here is the current position of the American Academy of Pediatrics (AAP) regarding the issue.

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